Aspirin treatment and platelet function in kawasaki disease

Abstract

The comparative effectiveness of small-dose (30 mg/kg) aspirin and highdose (150 mg/kg) in Kawasaki disease was evaluated in clinical symptoms and platelet aggregation. Twenty-three patients with Kawasaki disease were entered in the randomized study and devided into three groups. The durations of fever were 14.8 ± 3.5 days in the control group, 11.3 ± 2.1 d. in the small-dose group and 8.7 ± 2.3 d. in the high-dose group. The high-dose group showed a significantly shorter duration of fever (P