Secular Trends in Patent Ductus Arteriosus Management in Infants Born Preterm in the National Institute of Child Health and Human Development Neonatal Research Network

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Abstract

We evaluated changes in patent ductus arteriosus (PDA) diagnosis and treatment from 2012 through 2021 in a network of US academic hospitals. PDA treatment decreased among infants born at 26-28 weeks but not among infants born at 22-25 weeks. Rates of indomethacin use and PDA ligation decreased while acetaminophen use and transcatheter PDA closure increased.

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Kaluarachchi, D. C., Rysavy, M. A., Carper, B. A., Chock, V. Y., Laughon, M. M., Backes, C. H., … McNamara, P. J. (2024). Secular Trends in Patent Ductus Arteriosus Management in Infants Born Preterm in the National Institute of Child Health and Human Development Neonatal Research Network. Journal of Pediatrics, 266. https://doi.org/10.1016/j.jpeds.2023.113877

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