THE EFFECTS OF TRANSFLUTHRIN AS THE ACTIVE SUBSTANCE OF ONE PUSH AEROSOL REPELLENT ON ORGANS DAMAGE OF MICE (MUS MUSCULUS) (CASE STUDY OF LUNG, LIVER, BLOODS, AND KIDNEY)

Abstract

One push aerosol repellent used by the public contains an active substance called transfluthrin. Transfluthrin is mostly pyrethroid synthetic which has functions as neurotoxin substance. It may act as free radicals in the body due to the compounds which have one free electron that makes it reactive. The purpose of this study was to investigate the effects of transfluthrin on mice organs. In this study, the experimental animals (Wistar mice) were put in an exposure chamber and exposed by one push aerosol repellent contains around 20-25% of transfluthrin one time a day for 15 days. The damage of mice organs was identified by the microscopic picture (400x of magnification). The results showed that the expose of repellent contains about 20-25% of transfluthrin on mice increase the damage of lung, liver, blood, and kidney cells from 13% to 24%, 12% to 27%, 9% to 69% and 22% to 55%, respectively.