New antibiotic pigments related to fusarubin from fusarium solani (mart.) sacc.II. structure elucidations

Abstract

Three antibiotic pigments isolated from Fusarium solani and related to fusarubin (4) were shown to be O-ethylfusarubin (2), hydroxydihydrofusarubin (3) and O-ethylhydroxydihydrofusarubin (1). Recently a cholesterol-metabolizing fungus, isolated from soil and identified as Fusarium solani was shown to produce four antibiotic pigments of the fusarubin type1). Because of interest in their possible antitumor activity1,2) we decided to determine the structures of all four antibiotics. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.