Evaluation of continuous beam rescanning versus pulsed beam in pencil beam scanned proton therapy for lung tumours

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Abstract

The treatment of moving targets with pencil beam scanned proton therapy (PBS-PT) may rely on rescanning strategies to smooth out motion induced dosimetric disturbances. PBS-PT machines, such as Proteus®Plus (PPlus) and Proteus®One (POne), deliver a continuous or a pulsed beam, respectively. In PPlus, scaled (or no) rescanning can be applied, while POne implies intrinsic 'rescanning' due to its pulsed delivery. We investigated the efficacy of these PBS-PT delivery types for the treatment of lung tumours. In general, clinically acceptable plans were achieved, and PPlus and POne showed similar effectiveness.

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Ribeiro, C. O., Terpstra, J., Janssens, G., Langendijk, J. A., Both, S., Muijs, C. T., … Meijers, A. (2020). Evaluation of continuous beam rescanning versus pulsed beam in pencil beam scanned proton therapy for lung tumours. Physics in Medicine and Biology, 65(23). https://doi.org/10.1088/1361-6560/abc5c8

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