Clinical observation on palipeddone sustained release tablet in the treatment of schizophrenia

Abstract

Objective of this study was to evaluate the efficacy and adverse drug reactions (ADR) of palipeddone sustained release tablet in the treatment of schizophrenia in outpatients. Outpatients with schizophrenia treated with palipeddone sustained release tablet (observation group) in our hospital from Apr. to Sep. in 2009 were followed up and compared with those treated with risperidone (control group) during the same period. PANSS and TESS were applied to evaluate efficacy and ADR. Results suggest that the cure rates were 42.4% for control group and 49.6% for observation group. The effective rates were 74.8% for control group and 80.3% for observation group (P<0.05). As compared with control group, observation group showed slightly ADR with low frequency. In summary palipeddone sustained release tablet which has sound effect on schizophrenia with slightly ADR suits for outpatient treatment.