Microbial production of ursodeoxycholic acid from lithocholic acid by Fusarium equiseti M41

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Abstract

A fungus identified as F. equiseti was isolated from soil and found to carry out 7β-hydroxylation of lithocholic acid to ursodeoxycholic acid (35% yield; 350 mg/liter) in 112 h.

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Sawada, H., Kulprecha, S., & Nilubol, N. (1982). Microbial production of ursodeoxycholic acid from lithocholic acid by Fusarium equiseti M41. Applied and Environmental Microbiology, 44(6), 1249–1252. https://doi.org/10.1128/aem.44.6.1249-1252.1982

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