Covalent Binding to Tubulin by Isothiocyanates

  • Mi L
  • Xiao Z
  • Hood B
  • et al.
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Abstract

Isothiocyanates (ITCs) found in cruciferous vegetables, including benzyl-ITC (BITC), phenethyl-ITC (PEITC), and sulforaphane (SFN), inhibit carcinogenesis in animal models and induce apoptosis and cell cycle arrest in various cell types. The biochemical mechanisms ...

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Mi, L., Xiao, Z., Hood, B. L., Dakshanamurthy, S., Wang, X., Govind, S., … Chung, F.-L. (2008). Covalent Binding to Tubulin by Isothiocyanates. Journal of Biological Chemistry, 283(32), 22136–22146. https://doi.org/10.1074/jbc.m802330200

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