Mcr-1 colistin resistance in ESBL-producing Klebsiella pneumoniae, France

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Abstract

We report intestinal carriage of an extended-spectrum β-lactamase−producing Klebsiella pneumoniae strain with high-level resistance to colistin (MIC 24 mg/L) in a patient in France who had been hospitalized for fungal meningitis. The strain had the mcr-1 plasmid gene and an inactivated mgrB gene, which are associated with colistin resistance.

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Caspar, Y., Maillet, M., Pavese, P., Francony, G., Brion, J. P., Mallaret, M. R., … Maurin, M. (2017, May 1). Mcr-1 colistin resistance in ESBL-producing Klebsiella pneumoniae, France. Emerging Infectious Diseases. Centers for Disease Control and Prevention (CDC). https://doi.org/10.3201/eid2305.161942

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