Application of nano-composites in the recovery of sports ligament injury

Abstract

To study the application of nano-composites in the recovery of sports ligament injury is the main objective. Rabbits were divided into two groups on average. Firstly, cell samples were prepared after circumcision in children and nano-composite scaffolds were prepared by electrospinning driven by current. Cell samples were planted and cultured on nano-composite scaffolds to prepare nano-composite scaffolds mimicking extracellular matrix. The surgical sutures of the scaffolds were embedded in the injured motor ligaments. In the anterior cruciate ligament of the experimental sample, the experimental group was set up; in the control group, the experimental sample only received basic nursing care. At the 2nd w after operation, the tissue edema around the incision of knee joint was observed in the experimental group, no absorption of micro suture was observed, the gap between tendon and bone tunnel was obvious, the anterior cruciate ligament and tibia and femur bone were loose; at the 4th w after operation, the antibacterial micro suture partially absorbed the tissue edema of knee joint, there was no obvious gap between tendon-bone tunnel interface and anterior cruciate ligament. At the 8th w after operation, the edema of knee joint completely disappeared, the interface between tendon and bone tunnel was well repaired, most of the anti-bacterial micro sutures were absorbed and the anterior cruciate ligament and cancellous bone at the tibiofemoral junction were tightly bonded. Stem cell nano-composite fiber scaffolds can enhance the bonding strength of tendon-bone tunnel interface, promote the repair of tendon-bone tunnel interface and improve the maximum stiffness and tensile strength of tendon-bone tunnel interface in the experimental group, which indicates that stem cell nano-composite fiber scaffolds are active and effective in restoring injured ligaments.