Chemical genomics: dialed in transcriptional network control with non-steroidal glucocorticoid receptor modulators.

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Abstract

A recent study analyzed the transcriptional effects induced by a panel of non-steroidal glucocorticoid receptor modulators. The authors discover patterns of cell-, gene-, and mechanism-specific regulation, with implications for development of improved anti-inflammatory agents.

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Allen, J. J., & Shokat, K. M. (2006). Chemical genomics: dialed in transcriptional network control with non-steroidal glucocorticoid receptor modulators. ACS Chemical Biology, 1(3), 139–140. https://doi.org/10.1021/cb600137r

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