Skip to main content
Journal ArticleOPEN ACCESS

Myeloperoxidase exerts microbicidal activity against Mycobacterium tuberculosis

Infection and Immunity (1999) 67(8) 4149-4152
DOI: 10.1128/iai.67.8.4149-4152.1999
32Citations
Citations of this article
15Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

We investigated the antimycobacterial role of myeloperoxidase (MPO), one of the most abundant granule proteins in human neutrophils. Our data indicate that purified MPO, in the presence of hydrogen peroxide, exerts a consistent killing activity against Mycobacterium tuberculosis H37Rv and against a clinical isolate. The activity is time and dose dependent and requires the presence of chloride ions in the assay medium.

Cite

CITATION STYLE

APA

Borelli, V., Banfi, E., Perrotta, M. G., & Zabucchi, G. (1999). Myeloperoxidase exerts microbicidal activity against Mycobacterium tuberculosis. Infection and Immunity, 67(8), 4149–4152. https://doi.org/10.1128/iai.67.8.4149-4152.1999

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free