Preliminary study investigating brain shift compensation using 3D CBCT cerebral vascular images

Abstract

During a neurosurgical procedure, the exposed brain undergoes an elastic deformation caused by numerous factors. This deformation, also known as brain shift, greatly affects the accuracy of neuronavigation systems. Non-rigid registration methods based on point matching algorithms are frequently used to compensate for intraoperative brain shift, especially when anatomical structures such as cerebral vascular tree are available. In this work, we introduce a pipeline to compensate for the volumetric brain deformation with Cone Beam CT (CBCT) image data. Point matching algorithms are combined with Spline-based transforms for this purpose. The initial result of different combination is evaluated with synthetical image data.