RNA-Mediated Feedback Control of Transcriptional Condensates

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Abstract

During the early steps of transcription initiation, nascent RNAs stimulate transcriptional condensate formation, whereas the burst of RNAs produced during elongation stimulates condensate dissolution.

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Henninger, J. E., Oksuz, O., Shrinivas, K., Sagi, I., LeRoy, G., Zheng, M. M., … Young, R. A. (2021). RNA-Mediated Feedback Control of Transcriptional Condensates. Cell, 184(1), 207-225.e24. https://doi.org/10.1016/j.cell.2020.11.030

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