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JNK3 enzyme binding to arrestin-3 differentially affects the recruitment of upstream mitogen-activated protein (MAP) kinase kinases

Journal of Biological Chemistry (2013) 288(40) 28535-28547
DOI: 10.1074/jbc.M113.508085
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Abstract

Background:An interaction between arrestin-3 and MKK7 has never been elucidated. Results:Arrestin-3 directly binds MKK7 and promotes JNK3α2 phosphorylation by MKK7in vitroand in intact cells. Conclusion:Arrestin-3 recruits JNK3α2 and both upstream MKKs. Significance:Arrestin-3 promotes full JNK3α2 activation; MKK binding is regulated by JNK3α2. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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APA

Zhan, X., Kaoud, T. S., Kook, S., Dalby, K. N., & Gurevich, V. V. (2013). JNK3 enzyme binding to arrestin-3 differentially affects the recruitment of upstream mitogen-activated protein (MAP) kinase kinases. Journal of Biological Chemistry, 288(40), 28535–28547. https://doi.org/10.1074/jbc.M113.508085

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