9G DNAChip: Microarray based on the multiple interactions of 9 consecutive guanines

Abstract

We introduce the phenomenon of molecular recognition to immobilize oligonucleotides on AMCA slides for the production of 9G DNAChips. Facile and efficient method for the immobilization of the oligonucleotides appended with consecutive nine guanine bases is described. The 9G DNAChips shows more than 90% hybridization efficiency at 25°C in 30 min. © 2011 The Royal Society of Chemistry.