Regulation of neuronal morphogenesis and synaptic function by Abl family kinases

Abstract

Recent studies provide insights into the mechanisms by which Abelson non-receptor tyrosine kinases relay information from axon guidance and growth factor receptors to promote cytoskeletal rearrangements in developing neurons. Abelson non-receptor tyrosine kinases are also found in mature synapses, where their activities are required for optimal synaptic function.