Site-selective trifluoroacetylation of dimethylamino-substituted pyridines and its use as a building block for trifluoromethyl-containing heterocycles

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Abstract

Trifluoroacetyl pyridine derivatives are conveniently prepared, and applied to the synthesis of trifluoromethyl-substituted pyrazolo[4,3- c]pyridine derivatives.

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Kawase, M., Koyanagi, J., & Saito, S. (1999). Site-selective trifluoroacetylation of dimethylamino-substituted pyridines and its use as a building block for trifluoromethyl-containing heterocycles. Chemical and Pharmaceutical Bulletin, 47(5), 718–719. https://doi.org/10.1248/cpb.47.718

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