Distribution, function and predictive value of tumor-infiltrating γδ T lymphocytes

Abstract

Although γδ T cells are known to exert both tumor-preventing and tumor-promoting activity, there is still little information on the functional characteristics and clinical significance of γδ T cells isolated from the tumor site. In a recent study, we have investigated the distribution of different γδ T-cell populations in melanoma and their impact on disease outcome. © 2013 Landes Bioscience.