Efficacy of Ipomoea staphylina Roem and Schult. against dental and urinary infections

Abstract

The study was conducted to assess the efficacy of Ipomoea staphylina Roem and Schult. against dental and urinary infections employing several strains such as Staphylococcus aureus, S. saprophyticus, Escherichia coli, Chlamydia trachomatis, Citrobacter freundii, Acinetobacter baumannii, Mycoplasma limousine and Candida albicans. The activities were performed using aqueous, ethanol and petroleum ether extracts to determine the high inhibitory percentage and maximum zone of inhibition. In antiurolithiatic activity, the ethanol extract produced a maximum inhibitory percentage of 94.25\%. The ethanolic extract of I. staphylina resulted in maximum zone inhibition of 0.25 \& PLUSMN; 1.3 in 100 ml concentration against E. coli and C. albicans. Highest zone of inhibition (0.20 \& PLUSMN; 1.0 cm) in 100 ml concentration against S. saprophyticus was noted. In our present study, I. staphylina was potent against selected microbial pathogens, and hence could be beneficial in treating dental care and disorders of the urinary tract system thus providing a base for the design of future trials to determine its complete efficacy and safety for clinical use.