Appropriate antibiotic use for community-acquired pneumonia in inpatient settings and its impact on 30-days readmission and mortality rate

Abstract

Background: Community-Acquired Pneumonia (CAP) is a lower respiratory tract infection with bacteria as the most frequent causative agent. Therapy for pneumonia includes appropriate antibiotic usage. Inappropriate antibiotic use supposedly increase 30-days readmission and mortality rate. Objective: To evaluate the antibiotic use and the impact of appropriate antibiotic use on the 30-days readmission and mortality of CAP patients in inpatient non-ICU settings. Method: A cross-sectional, analytic study was conducted. We collected data from Universitas Airlangga hospital’s medical record to obtain the details of antibiotic usage. Result were evaluated using the Gyssens algorithm. A chi-square test was used to identify the impact of appropriate antibiotic use on the 30-days readmission and mortality. Result: A total of 90 patients with CAP fulfilled the inclusion criteria. One gram of ceftriaxone IV was the most prescribed antibiotic for therapy of CAP. The amount of appropriate antibiotic use is 85.6%. Five patients (5.6%) went through the 30-days readmission. There was no death reported. The statistical test between antibiotic use and 30-days readmission obtained p value=0.894 (p>0.05). Conclusion: There was no significant impact of appropriate antibiotic use on the 30-days readmission rate and the mortality rate could not be assessed.