Epidemiology of critical states during pregnancy after assisted reproductive technologies

Abstract

Aim: The aim of this research was to have a thorough study of predictors of critical states during pregnancy after assisted reproductive technologies. Materials and methods: A retrospective study of 303 patients with “near-miss,” out of which 37 are pregnancy cases after ART (the main group) and 265 are spontaneous pregnancy cases (the control group). Results: Pregnancy after ART constituted 12.3% of all critical states. In the main group (10.8%), severe ovarian hyperstimulation prevailed over all possible reasons for critical states within the period of up to 22 weeks of gestation, whereas bleeding predominated in the control group (57.1%). When pregnancy terms exceeded 22 weeks, the leading reason for “near-miss” in the main group was preeclampsia (59.5%) with underlying thrombophilia (29.7%) and gestation pancreatic diabetes (32.4%); bleeding was the main factor in the control group (36.6%). Conclusion: Women after assisted reproductive technologies constitute a high-risk group for critical obstetric states not only in the nearest time period but also long after ART.