Laser Correlation Spectroscopy: Nutritional, Ecological and Toxic Aspects

Abstract

Changes in physiological status of the organism under the effect of environmental factors modulate metabolic processes, which in turn, affects the composition of biological fluids and possibly of bioelements – substances, important for building and maintenance of the living matter. Bioelements are the elemental functioning units of living matter, which are biologically active complexes of chemical elements as atoms, ions and nanoparticles with organic compounds of exogenous (primary) or biogenous (secondary) origin (Skalny, 2009, 2011). Evaluation of subfraction composition of samples provides information on percentage of biosubstrate constituents and yields integral characteristics reflecting the function of systems and their readiness to adequate protection of the body. This initially biophysical method, named laser correlation spectroscopy (LCS) is used for screening of large groups of conventionally healthy individuals for diagnosis of body functional strain and detection of risk groups (Karganov et al., 2009). Optimized software takes into account individual peculiarities in internal sanogenetic systems of the organism when determining consequences for health in persons exposed to low doses of potentially harmful factors (Kryzhanovsky, 2004). LCS allows measuring particle size in native biological fluids. It is successfully used in clinical practice for evaluation of the disease severity and treatment efficiency in patients with asthma, diabetes mellitus, myasthenia, some haematological diseases, and other pathologies (Kovalev et al., 2002; Piruzyan et al., 2004; Karganov et al., 2006).