Prevalence and bacterial spectrum of urinary tract infection in nephrotic syndrome: a cross sectional study from a tertiary care centre

Abstract

The analysis of nonlinear delay-differential equations (DDEs) subjected to external forcing is difficult due to the infinite dimensionality of the space in which they evolve. To simplify the analysis of such systems, the present work develops a non-homogeneous center manifold (CM) reduction scheme, which allows the derivation of a time-dependent order parameter equation in finite dimension. This differential equation captures the major dynamical features of the delayed system. The forcing is assumed to be small compared to the amplitude of the autonomous system, in order to cause only small variations of the fixed points and of the autonomous CM. The time-dependent CM is shown to satisfy a non-homogeneous partial differential equation. We first briefly review CM theory for DDEs. Then we show, for the general scalar case, how an ansatz that separates the CM into one for the autonomous problem plus an additional time-dependent order-two correction leads to satisfying results. The paper then details the application to a transcritical bifurcation subjected to single or multiple periodic forcings. The validity limits of the reduction scheme are also highlighted. Finally, we characterize the specific case of additive stochastic driving of the transcritical bifurcation, where additive white noise shifts the mode of the probability density function of the state variable to larger amplitudes.