Simultaneous antibacterial and anticoagulant properties of polypropylene non-woven textiles

Abstract

The aim of this work was to prepare a non-woven Polypropylene (PP) textile functionalized with bioactive molecules to improve simultaneously its anticoagulation and antibacterial properties. The immobilization of either heparin (anticoagulation agent) or gentamicin (aminoglycoside antibiotic) was already proven to be effective on non-woven PP textiles. This work details how we managed to immobilize both gentamicin and heparin on the textile [1]. The immobilization times were studied in order to determine the best compromise between cytocompatibility, anticoagulant effect and antimicrobial activity. © Owned by the authors, published by EDP Sciences, 2013.