Parkinsonism, tremor, and depression induced by cinnarizine and flunarizine

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Abstract

Cinnarizine and flunarizine are piperazine derivatives with antihistamine properties and calcium channel blocking activity. Several recent reports have described extrapyramidal reactions and depression associated with their use.

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Capella, D., Laporte, J. R., Castel, J. M., Tristan, C., Cos, A., & Morales-Olivas, F. J. (1988). Parkinsonism, tremor, and depression induced by cinnarizine and flunarizine. British Medical Journal, 297(6650), 722–723. https://doi.org/10.1136/bmj.297.6650.722

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