Abstract
Polyglutamine diseases are a major group of neurodegeneration induced by mutant proteins containing an expanded polyglutamine tract sequence. In this chapter, recent findings on aggregation process and metabolism of mutant proteins are summarized. In addition, the development of molecular therapeutics against polyglutamine diseases are discussed. © 2007 Springer-Verlag US.
Cite
CITATION STYLE
APA
Okazawa, H. (2007). Polyglutamine diseases. In Handbook of Neurochemistry and Molecular Neurobiology: Neural Protein Metabolism and Function (pp. 355–369). Springer US. https://doi.org/10.1007/978-0-387-30379-6_12
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
Already have an account? Sign in
Sign up for free