Human coronavirus NL63 in hospitalized children with respiratory infection: A 2-year study from Chongqing, China

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Abstract

Human coronavirus (HCoV) NL63, a newly discovered coronavirus, has been associated with acute lower respiratory tract infections (ALRTI). We detected HCoV-NL63 via reverse transcriptional PCR (RT-PCR) in eight out of 878 respiratory specimens freshly collected from hospitalized children with ALRTI between April 2006 and March 2008 in Children's Hospital of Chongqing Medical University. Peak of HCoV-NL63 activity often appeared during the summer and autumn in Chongqing area. All children with HCoV-NL63 infection were <1 year of age. The diagnosis included bronchial pneumonia, bronchitis, interstitial pneumonia and bronchiolitis. All children recovered.

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Xin, C., Yong, Z. Z., Yan, L., & Dong, Z. X. (2012). Human coronavirus NL63 in hospitalized children with respiratory infection: A 2-year study from Chongqing, China. Indian Pediatrics, 49(10), 825–828. https://doi.org/10.1007/s13312-012-0194-1

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