Interspecies Transmission of Feline Immunodeficiency Virus from the Domestic Cat to the Tsushima Cat ( Felis bengalensis euptilura ) in the Wild

Abstract

Feline immunodeficiency virus (FIV) was isolated from a wild-caught Tsushima cat ( Felis bengalensis euptilura ), an endangered Japanese nondomestic subspecies of leopard cat ( F. bengalensis ). Phylogenetic analysis of the env gene sequences indicated that the FIV from the Tsushima cat belonged to a cluster of subtype D FIVs from domestic cats. FIVs from both the Tsushima cat and the domestic cat showed similar levels of replication and cytopathicity in lymphoid cell lines derived from these two species. The results indicated the occurrence of interspecies transmission of FIV from the domestic cat to the Tsushima cat in the wild.