Green Techniques to Synthesize Schiff Bases

Abstract

From ancient times, the chemistry of Schiff base-containing molecules has been a fascinating subject of study. They've been found to be a flexible pharmacophore for the creation and development of a wide range of bioactive lead compounds. Schiff bases are compounds containing the imine functional group. Different Schiff base containing byproducts have recently been synthesized and studied for activities such as antioxidant, antibacterial, antituberculosis, anti-inflammatory, antidepressant and anxiolytic activity, antihypertensive, anticonvulsants, anticancer, and antifungal activity. Different green chemistry techniques like-solid state, sonochemical, microwave assisted synthesis for synthesis of Schiff bases are discussed in this review.