Effective Treatment of Chronic Hepatitis C Virus Infection with Ledipasvir/Sofosbuvir in 2 Teenagers with HIV Coinfection: A Brief Report

Abstract

Abstract: We present the efficacy and safety of 12 weeks of therapy with a fixed dose of ledipasvir/sofosbuvir in 2 teenagers with HIV/hepatitis C virus coinfection. Patient 1 presented with compensated cirrhosis, whereas patient 2 had evidence of previous hepatitis B virus infection. Both patients achieved a sustained virologic response 12 weeks after the end of treatment. No serious adverse effects were reported.