Stachybotrin C and parvisporin, novel neuritogenic compounds. I. Taxonomy, isolation, physico-chemical and biological properties

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Abstract

Stachybotrin C and parvisporin, novel neuritogenic compounds, were isolated from the culture broth of Stachybotrys parvispora F4708. Stachybotrin C induced significant neurite outgrowth in PC12 cells and showed cell survival activity in the primary culture of cerebral cortical neurons. Parvisporin demonstrated only weak neuritogenic activity.

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Nozawa, Y., Yamamoto, K., Ito, M., Sakai, N., Mizoue, K., Mizobe, F., & Hanada, K. (1997). Stachybotrin C and parvisporin, novel neuritogenic compounds. I. Taxonomy, isolation, physico-chemical and biological properties. Journal of Antibiotics, 50(8), 635–640. https://doi.org/10.7164/antibiotics.50.635

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