Abstract
Copper catalyzed Alkyne Azide 1,3-dipolar cycloaddition (CuAAC) "click reaction" was applied for the construction of oligonucleotide conjugates, circular objects and phosphodiester glyco-clusters. To this end, several strategies were developed to introduce either alkyne or azide functions into an oligonucleotide.
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CITATION STYLE
APA
Morvan, F., Meyer, A., Pourceau, G., Vidal, S., Chevolot, Y., Souteyrand, E., & Vasseur, J. J. (2008). Click chemistry and oligonucleotides: how a simple reaction can do so much. Nucleic Acids Symposium Series (2004), (52), 47–48. https://doi.org/10.1093/nass/nrn024
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