One-pot nitration of phenols under mild and heterogeneous conditions

Abstract

Nitrophenols can be obtained via nitrosation-oxidation of phenols with Oxone®, NaNO2 and wet SiO2 at room temperature in moderate to high yields. In situ generation of HNO2 and the radical cation mechanism via the nitrous acid catalysed (NAC) pathway or hydrogen abstraction involving NO2 appear to be applicable to phenol nitration using these reagents.