Progress and current trends in the electrochemical determination of phosphate ions for environmental and biological monitoring applications

Abstract

The determination of phosphate ions in biological testing is critical for environmental safety. A reliable and accurate method is required to measure the true phosphate ion concentrations; in this regard, the electrochemical method is preferable because of its simple operation, fast response, and high sensitivity. By compiling existing electroanalytical techniques, researchers can compare the advantages and disadvantages of each method. This review examines the progress and recent advances in electrochemical sensing strategies adapted for the determination of phosphate ions in the environmental and during biological monitoring. We first discuss the history of phosphorus and the development of methods to detect phosphates. The recognition elements of phosphate ion sensors for environmental applications include metal-based, nanomaterial-based, carbon-based, and enzymatic electrodes. Phosphate determination in biological samples, such as blood serum, drugs, and other biological fluids, such as urine and saliva, as well as phosphate esters, is also discussed. The final part of our review addresses the current challenges that phosphate sensing technology faces and illustrates future opportunities for more reliable phosphate detection. Graphical abstract: [Figure not available: see fulltext.]