Influence of sinus rhythm restoration and maintenance on left ventricle diameter and function in patients with persistent atrial fibrillation - One year follow-up

Abstract

Aim of our study was to determine the dynamics of selected echocardiographic parameters after sinus rhythm (SR) restoration and maintenance in pts with persistent nonvalvular atrial fibrillation (AF) during one year follow-up period. Material and methods: Our study population comprised 104 pts (F/M 33/71; mean age 60.4 ± 7.4) assigned to SR restoration and maintenance with serial antiarrhythmic drug usage, for whom transthoracic echocardiographic (TTE) variables were recorded prior to, 2 and 12 months after cardioversion (CD). Left ventricle diastolic diameter and fractional shortening were variables of interest. Results: SR was presented in 66 (63.5%) pts at one year. There was no significant differences in left ventricle diastolic diameter during the follow up. A significant increase in left ventricular fractional shortening (29.9 ± 6.9% vs 34.5 ± 8.9%; p<0.001) was found in pts assigned to the sinus rhythm restoration according to intension-to-treat analysis. Such treand was noted only in pts who maintained SR during the follow up (29.9 ± 7.6% vs 35.6 ± 9.3%; p<0.001). Conclusions: Among all considered variables only value of left ventricular fractional shortening , incrased after successful CV of persistent AF in one year follow-up.