Latent hepatitis B diagnostic approach improvement in blood donors

Abstract

Aim. The improvement of the target algorithm for diagnosing latent hepatitis B based on the results of a screening examination of blood donors. Material and methods. The analysis of regulatory documents was carried out. The cards of donors taken away from the donation were analyzed selectively (n=840). Research the change line of the hepatitis B incidence in the Republic of Tatarstan population for 2010-2020. Results. Despite the decrease in the incidence of viral hepatitis B among the Republic of Tatarstan population, the detection rate of anti-HBcor in the donor group is 38 cases per 1000 donors in 2010 and 4 cases in 2020, including 4 cases with anti-HBcorIgM and 1 case per 1000 donors respectively. Conclusion. The introduction of the latent hepatitis B diagnosis and dispensary monitoring of donors with suspected latent infection into clinical practice requires close cooperation between an infectious disease specialist, a transfusiologist and a hospital epidemiologist to prescribe an extended diagnostic examination and identify therapy (including antiviral) with a mandatory epidemiological investigation of the focus hepatitis in each case diverted from blood donation.