Generation of arynes by selective cleavage of a carbonphosphorus bond of o-(diarylphosphinyl)aryl triflates using a grignard reagent

Abstract

A novel method for generating arynes, including disubsti-tuted benzynes and a dehydrophenoxathiin, is reported. The treatment of easily synthesizable o-(diarylphosphinyl)aryl triflates having two electron-deficient aromatic groups on the phosphorus atom with a phenyl Grignard reagent triggered the efficient generation of arynes by selective cleavage of a carbonphosphorus bond.