The wettability of electron spun membranes by synovial fluid

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Abstract

Aseptic loosening due to periprosthetic osteolysis has been accepted as one of the leading causes of revision procedures in patients with previous joint arthroplasty. Recently, several strategies for suppression of osteolysis were proposed, mostly based on biological treatment such as mitigation of chronic inflammatory reactions. However, these biological treatments do not stop the debris migration but only reduce the inflammatory reaction. To address this shortcoming, we propose the concept of ultrahigh molecular weighted polyethylene particles filtration storage by electrospun membranes. Firstly, the surface tension of synovial fluid (SF) is obtained by use of a pendant droplet. Secondly, the contact angle of the electrospun membranes wetted by two different liquids is measured to obtain the free surface energy using of the Owens-Wendt model. Additionally, the wettability of electrospun membranes by SF as a function of technology parameters is studied.

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Hrouda, A., Jirkovec, R., Hamrikova, P., Vanierschot, M., Denis, K., & Capek, L. (2021). The wettability of electron spun membranes by synovial fluid. Royal Society Open Science, 8(12). https://doi.org/10.1098/rsos.210892

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