The nucleosome serves as a general gene repressor by the occlusion of regulatory and promoter DNA sequences. Repression is relieved by the SWI/SNF-RSC family of chromatin-remodeling complexes. Research reviewed here has revealed the essential features of the remodeling process.
CITATION STYLE
Lorch, Y., & Kornberg, R. D. (2015, July 16). Chromatin-remodeling and the initiation of transcription. Quarterly Reviews of Biophysics. Cambridge University Press. https://doi.org/10.1017/S0033583515000116
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