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Changes in drug metabolism with increasing age: 1. warfarin binding and plasma proteins.

British Journal of Clinical Pharmacology (1975) 2(1) 69-72
DOI: 10.1111/j.1365-2125.1975.tb00474.x
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Abstract

1 A decrease was found in the binding capacity of elderly people for warfarin. 2 The decrease in binding correlated with a fall in plasma albumin concentrations. 3 No changes in the association constant were observed. 1975 Blackwell Science Ltd

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Hayes, M., Langman, M., & Short, A. (1975). Changes in drug metabolism with increasing age: 1. warfarin binding and plasma proteins. British Journal of Clinical Pharmacology, 2(1), 69–72. https://doi.org/10.1111/j.1365-2125.1975.tb00474.x

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