Phenolic constituents from the tree barks of garcinia cf cymosa and their antioxidant and antibacterial activities

Abstract

Two isoprenylated xanthones, α-mangostin (1) and β-mangostin (2) were isolated from the tree barks of Garcinia cf cymosa, along with the flavanol epicatechin (3). Their structures were elucidated by analysis of spectroscopic data. Compounds 1-3 exhibited moderate in vitro antibacterial activity against Staphylococcus aureus and Bacillus sp, while in the 1,2-diphenyl-picryl-hydrazyl (DPPH) antioxidant assay system only compound 3 showed moderate free radical scavenging activity, with IC50 value of 41.8 ppm.