Spontaneous Hematomas and Deep Vein Thrombosis during the Recovery from a SARS‐CoV‐2 Infection: Case Report and Literature Review

Abstract

Background: The frequent occurrence of thromboembolic events in patients infected with the severe acute respiratory syndrome CoV2 (SARS‐CoV‐2) virus is a well‐recognized fact in the medical literature, but less data is available about possible hemorrhagic incidents. Methods: We report the case of a 76‐year‐old patient who suffered from a mild COVID‐19 infection in September 2021 and after four weeks, experienced a completely spontaneous popliteal hematoma followed by deep vein thrombosis (DVT). Therapy with low molecular weight heparins (LMWH) was started, but subsequently, the patient developed a massive sub‐pectoral and calf hematoma leading to moderate post‐hemorrhagic anemia and acute kidney injury. This patient was treated completely con-servatively. Conclusions: Considering the continuous spread of the infection with various, continu-ously evolving strains of this virus and the extended use of LWMH in clinical practice, such cases were seldom described in the medical literature, but should be considered as a potential cause for hemorrhagic events.