Sjögren's syndrome: Studying the disease in mice

Citations of this article
Mendeley users who have this article in their library.

This artice is free to access.


Sjögren's syndrome (SS), a systemic autoimmune disease, is characterized by inflammation of exocrine tissues accompanied by a significant loss of their secretory function. Clinical symptoms develop late and there are no diagnostic tests enabling early diagnosis of SS. Thus, particularly to study these covert stages, researchers turn to studying animal models where mice provide great freedom for genetic manipulation and testing the effect of experimental intervention. The present review summarizes current literature pertaining to both spontaneous and extrinsic-factor induced SS-like diseases in mouse models, discussing advantages and disadvantages related to the use of murine models in SS research. © 2011 BioMed Central Ltd.




Delaleu, N., Nguyen, C. Q., Peck, A. B., & Jonsson, R. (2011, June 13). Sjögren’s syndrome: Studying the disease in mice. Arthritis Research and Therapy.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free