ATLANTIC DIP: Despite insulin therapy in women with IADPSG diagnosed GDM, desired pregnancy outcomes are still not achieved. What are we missing?

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Abstract

Aims To assess if pregnancy outcomes for women with GDM treated with insulin (GDM-I) are comparable to outcomes for women with GDM treated with medical nutritional therapy (MNT) (GDM-M). Materials and methods This retrospective cohort study included 752 women with GDM-I and 567 women with GDM-M. Maternal and foetal outcomes were examined. Results Women with GDM-I had a greater risk of polyhydramnios (aOR 2.33, 95%CI 1.31–4.14) and were more likely to deliver by caesarean section (CS) (aOR 1.67, 95%CI 1.25–2.23). Their offspring had higher rates of macrosomia (22.2% vs 12.7%; p

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Bogdanet, D., Egan, A., Reddin, C., Kirwan, B., Carmody, L., & Dunne, F. (2018). ATLANTIC DIP: Despite insulin therapy in women with IADPSG diagnosed GDM, desired pregnancy outcomes are still not achieved. What are we missing? Diabetes Research and Clinical Practice, 136, 116–123. https://doi.org/10.1016/j.diabres.2017.12.003

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