In vitro synergy testing using levofloxacin (LVX) plus piperacillin/tazobactam (TZP) was performed by Etest and time-kill assay (TKA) for 31 unique fluoroquinolone-resistant Pseudomonas aeruginosa isolates. The Etest method showed synergy for 9/31 (29%) of isolates, while TKA showed synergy with 14/31 (45%) of isolates. When comparing the Etest method and TKA, concordant results for synergy, antagonism, and indifference were obtained for 24/31 (77%) of the isolates tested.
CITATION STYLE
Chachanidze, V., Curbelo-Irizarry, A., Ashcraft, D., & Pankey, G. (2009). In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa. Interdisciplinary Perspectives on Infectious Diseases, 2009, 1–5. https://doi.org/10.1155/2009/984934
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