Development of near infrared-fluorescent nanophosphors and applications for cancer diagnosis and therapy

30Citations
Citations of this article
41Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

The use of near infrared (NIR) light for biomedical photonics in the wavelength region between 800 and 2000nm, which is called "biological window", has received particular attention since water and biological tissues have minimal optical loss due to scattering and absorption as well as autofluorescence in this region. Recent development of InGaAs CCD enables observations in this wavelength region. In the present paper, we report development of Yb and Er-doped yttrium oxide nanoparticles (Y2 O 3:YbEr-NP) which show strong NIR emission under NIR excitation (NIR-NIR emission). We also demonstrate that NIR emission can be observed through swine colon wall. Based on these results, we propose a possible application of Y2 O3:YbEr-NP for cancer diagnosis and therapy using NIR-NIR imaging system. Our results also suggest potential applications of Y2 O3:YbEr-NP for noninvasive detection of various diseases. Copyright © 2010 Tamotsu Zako et al.

Cite

CITATION STYLE

APA

Zako, T., Hyodo, H., Tsuji, K., Tokuzen, K., Kishimoto, H., Ito, M., … Soga, K. (2010). Development of near infrared-fluorescent nanophosphors and applications for cancer diagnosis and therapy. Journal of Nanomaterials, 2010. https://doi.org/10.1155/2010/491471

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free