EBV-associated gastric carcinoma in high- and low-incidence areas for nasopharyngeal carcinoma

Abstract

Background: Approximately 10 of gastric carcinomas are associated with Epstein-Barr virus (EBV). The Inuit in Greenland have a high incidence of EBV-associated nasopharyngeal carcinoma. Methods: We conducted a population-based case-control study comparing gastric carcinomas in Greenland and in Denmark. Results: The prevalence rate of EBV-associated gastric carcinomas was 8.5 in both populations. Conclusion: The findings of this study argue against a general susceptibility to EBV-associated carcinomas among the Inuit. © 2009 Cancer Research UK All rights reserved.