Results of a Multinational Study Suggest the Need for Rapid Diagnosis and Early Antiviral Treatment at the Onset of Herpetic Meningoencephalitis

Hakan Erdem; Yasemin Cag; Derya Ozturk-Engin; Sylviane Defres; Selcuk Kaya; Lykke Larsen; Mario Poljak; Bruno Barsic; Xavier Argemi; Signe Maj Sørensen; Anne Lisbeth Bohr; Pierre Tattevin; Jesper Damsgaard Gunst; Lenka Baštáková; Matjaž Jereb; Isik Somuncu Johansen; Oguz Karabay; Abdullah Umut Pekok; Oguz Resat Sipahi; Mahtab Chehri; Guillaume Beraud; Ghaydaa Shehata; Rosa Fontana Del Vecchio; Mauro Maresca; Hasan Karsen; Gonul Sengoz; Mustafa Sunbul; Gulden Yilmaz; Hava Yilmaz; Ahmad Sharif-Yakan; Souha Shararah Kanj; Emine Parlak; Filiz Pehlivanoglu; Fatime Korkmaz; Suheyla Komur; Sukran Kose; Mehmet Ulug; Sibel Bolukcu; Seher Ayten Coskuner; Nevin Ince; Yasemin Akkoyunlu; Gulistan Halac; Elif Sahin-Horasan; Hulya Tireli; Gamze Kilicoglu; Akram Al-Mahdawi; Salih Atakan Nemli; Asuman Inan; Seniha Senbayrak; Jean Paul Stahl; Haluk Vahaboglu

Journal ArticleOPEN ACCESS

Results of a Multinational Study Suggest the Need for Rapid Diagnosis and Early Antiviral Treatment at the Onset of Herpetic Meningoencephalitis

Erdem H
Cag Y
Ozturk-Engin D
et al.

Antimicrobial Agents and Chemotherapy (2015) 59(6) 3084-3089

DOI: 10.1128/AAC.05016-14

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66Readers

Abstract

7 days (OR, 3.75; 95% CI, 1.72 to 8.15) until the commencement of treatment predicted unfavorable outcomes. The outcome in HME patients is related to a combination of therapeutic and host factors. This study suggests that rapid diagnosis and early administration of antiviral treatment in HME patients are keys to a favorable outcome.

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Erdem, H., Cag, Y., Ozturk-Engin, D., Defres, S., Kaya, S., Larsen, L., … Vahaboglu, H. (2015). Results of a Multinational Study Suggest the Need for Rapid Diagnosis and Early Antiviral Treatment at the Onset of Herpetic Meningoencephalitis. Antimicrobial Agents and Chemotherapy, 59(6), 3084–3089. https://doi.org/10.1128/AAC.05016-14

Results of a Multinational Study Suggest the Need for Rapid Diagnosis and Early Antiviral Treatment at the Onset of Herpetic Meningoencephalitis

Abstract

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