Flow visualization as a complementary tool to hemolysis testing in the development of centrifugal blood pumps

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Abstract

With a 250% scaled-up pump model, high speed video camera, and argon ion laser light sheet, flow patterns related to hemolysis were visualized and analyzed with 4 frame particle tracking software. Different flow patterns and shear distributions were clarified by flow visualization for pumps modified to have different hemolysis levels. A combination of in vitro hemolysis tests, flow visualization, and CFD analysis suggested a close relationship between hemolysis and high shear caused by small impeller/casing gaps. Because arbitrary cross sections can be illuminated by laser light sheet, flow visualization is a useful tool in finding locations related to hemolysis in the design process of rotary blood pumps.

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Yamane, T., Asztalos, B., Nishida, M., Masuzawa, T., Takiura, K., Taenaka, Y., … Ito, K. (1998). Flow visualization as a complementary tool to hemolysis testing in the development of centrifugal blood pumps. Artificial Organs, 22(5), 375–380. https://doi.org/10.1046/j.1525-1594.1998.06126.x

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